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Antibodies

Anti-Hu CD107a Pacific Blue[TM]

Product Sizes
25 tests
£176.00
PB-671-25TESTS
100 tests
£312.00
PB-671-100TESTS
About this Product
SKU:
PB-671
Application:
Flow Cytometry
CE/IVD:
RUO
translate.label.attr.clone:
H4A3
Conjugate:
Pacific Blue™
Extra Details:
CD107a (lysosome-associated membrane protein-1, LAMP-1), together with LAMP-2, is a major constituent of lysosomal membrane, 1-2% of total CD107a is found also on the plasma membrane. The LAMP proteins are involved in lysosome biogenesis and are required for fusion of lysosomes with phagosomes. Increased CD107a immunoreactivity is observed in neurones, and in glial cells surrounding senile plaques in Alzheimers disease cases and is localized mainly in medullary epithelial cells, single macrophages and lymphocytes in acute thymic involution. CD107a is a good marker of mast cell activation.
Immunogen:
Human PBMC
Isotype:
IgG1, kappa
Reactivities:
Human, Mouse, Non-human Primate
Shipping Conditions:
Blue Ice
Specificity:
The mouse monoclonal antibody H4A3 recognizes an extracellular/luminal epitope of CD107a, an approximately 100-120 kDa glycoprotein expressed mainly on lysosomal, but also on the plasma membrane.
Storage Conditions:
2-8[o]C Do not freeze. Protect from light.
Supplier:
Exbio
Type:
Antibody
FluoroFinder: