Anti-Hu CD117 Alexa Fluor[R] 700
Product Sizes
100 tests
£312.00
A7-586-100TESTS
About this Product
- SKU:
- A7-586
- Application:
- Flow Cytometry
- CE/IVD:
- RUO
- translate.label.attr.clone:
- 104D2
- Conjugate:
- Alexa Fluor® 700
- Extra Details:
- CD117 / c-Kit (stem cell factor receptor) is a 145 kDa receptor tyrosine kinase that regulates cell proliferation, adhesion, chemotaxis, apoptosis and other cell processes. Mutations of CD117 / c-Kit can lead to growth and progression of tumours. After binding of its ligand, SCF (stem cell factor), CD117 / c-Kit is autophosphorylated on its intracellular domains and activated. CD117 is expressed on pluripotent hematopoietic progenitor cells, mast cells and various cancer cells, e.g. acute myeloid leukemia cells.
- Immunogen:
- MOLM-1 megakaryocytic cells
- Isotype:
- IgG1, kappa
- Reactivities:
- Bovine, Human, Non-human Primate
- Shipping Conditions:
- Blue Ice
- Specificity:
- The mouse monoclonal antibody 104D2 detects extracellular part of CD117 / c-Kit protooncogen.
- Storage Conditions:
- 2-8[o]C Do not freeze. Protect from light.
- Supplier:
- Exbio
- Type:
- Antibody
- FluoroFinder:
