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Antibodies

Anti-Hu CD11c Alexa Fluor[R] 700

Product Sizes
100 tests
£312.00
A7-529-100TESTS
About this Product
SKU:
A7-529
Application:
Flow Cytometry
CE/IVD:
RUO
translate.label.attr.clone:
BU15
Conjugate:
Alexa Fluor® 700
Extra Details:
CD11c (p150, alphaX integrin subunit) forms complex with CD18 (beta2 integrin subunit) and is expressed mainly on tissue macrophages and dendritic cells. CD11c binds to complement fragment iC3b, fibrinogen, VCAM-1 and ICAM-2 or e.g. CD90. Like other beta2 integrins, CD11c/CD18 plays roles in cell migration and phagocytosis. Moreover, interaction of CD11c/CD18 with plasminogen regulates plasmin activities, and interaction with heparin counteracts binding of iC3b.
Immunogen:
Dendritic cells of synovial fluid
Isotype:
IgG1, kappa
Reactivities:
Human, Non-human Primate
Shipping Conditions:
Blue Ice
Specificity:
The antibody BU15 reacts with an extracellular epitope of CD11c (alphaX, p150), a 150 kDa integrin expressed mainly on dendritic cells and tissue macrophages.
Storage Conditions:
2-8[o]C Do not freeze. Protect from light.
Supplier:
Exbio
Type:
Antibody
FluoroFinder: