Anti-PPM1D Alexa Fluor[R] 647
Product Sizes
0.1 mg
£312.00
A6-894-0.1MG
About this Product
- SKU:
- A6-894
- Application:
- Flow Cytometry, IHC-Paraffin, Immunocytochemistry
- CE/IVD:
- RUO
- translate.label.attr.clone:
- 7E11/C5
- Conjugate:
- Alexa Fluor® 647
- Concentration:
- 0.1 mg/ml
- Extra Details:
- PPM1D is a Mg2+/Mn2+ dependent protein phosphatase 1D with inducible expression in response to various types of environmental stress. This expression is p53-dependent, and subsequently PPM1D negatively regulates the p53-mediated transcription, thus it suppresses the apoptosis. PPM1D contributes to development of carcinomas, and seems to be a promissing therapeutic target. Amplification of PPM1D is associated with breast cancer.
- Immunogen:
- Purified human PPM1D
- Isotype:
- IgG1
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Specificity:
- The mouse monoclonal antibody 7E11/C5 recognizes an epitope within the sequence FTNEDELYNLLTDSP of PPM1D, a protein phosphatase, which contributes to development of some carcinomas.
- Storage Conditions:
- 2-8[o]C Do not freeze. Protect from light.
- Supplier:
- Exbio
- Type:
- Antibody
- FluoroFinder:
