Anti-Galectin-3 Alexa Fluor[R] 488
Product Sizes
0.1 mg
£312.00
A4-876-0.1MG
About this Product
- SKU:
- A4-876
- Application:
- Flow Cytometry, IHC-Paraffin, Immunocytochemistry
- CE/IVD:
- RUO
- translate.label.attr.clone:
- M3/38
- Conjugate:
- Alexa Fluor® 488
- Concentration:
- 0.1 mg/ml
- Extra Details:
- Galectin-3 is a galactose-binding lectin, which modulates intercellular interactions and interactions of the cell with ECM, as well as it is a nuclear protein and a component of inner mitochondrial membrane. Galectin-3 binds IgE, and takes part in formation of immunological synapse. It is detected cytoplasmatically in adenomas and carcinomas by immunohistochemistry. It is expressed in colonic and intestinal epithelium, papillary and follicular carcinomas, neoplastic astrocytes, inflammatory macrophages, and some lymphocytes. Upregulation of galectin-3 is involved in cancer progression and metastasis.
- Immunogen:
- murine galectin-3
- Isotype:
- IgG2a, kappa
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Specificity:
- The rat monoclonal antibody M3/38 recognizes an epitope within amino acids 40-100 in N-terminal domain of murine galectin 3, a 35 kDa lectin expressed both intracellularly, and after its secretion also on the cell surface.
- Storage Conditions:
- 2-8[o]C Do not freeze. Protect from light.
- Supplier:
- Exbio
- Type:
- Antibody
- FluoroFinder:
