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Antibodies

Anti-Hu CD35 Alexa Fluor[R] 488

Product Sizes
100 tests
£312.00
A4-703-100TESTS
About this Product
SKU:
A4-703
Application:
Flow Cytometry, Immunocytochemistry
CE/IVD:
RUO
translate.label.attr.clone:
E11
Conjugate:
Alexa Fluor® 488
Extra Details:
CD35 (complement receptor 1, CR1) is a monomeric multiple modular cell surface glycoprotein which serves as receptor for C3b and C4b, the most important components of the complement system leading to clearance of foreign macromolecules. It is expressed mainly on the surface of granulocytes, monocytes, erythrocytes, B cells and folicular dendritic cells. Besides its role in complement cascade, CD35 is involved in blocking BCR-induced proliferation and the differentiation of B cells to plasmablasts and their Ig production.
Immunogen:
Acute monocytic leukemia cells and normal blood monocytes
Isotype:
IgG1
Reactivities:
Human, Non-human Primate
Shipping Conditions:
Blue Ice
Specificity:
The mouse monoclonal antibody E11 recognizes an extracellular epitope of CD35 (CR1), a type I transmembrane glycoprotein expressed on granulocytes, monocytes, B cells, folicular dendritic cells, erythrocytes, NK and T cell subsets, as well as e.g. on glomerulal podocytes.
Storage Conditions:
2-8[o]C Do not freeze. Protect from light.
Supplier:
Exbio
Type:
Antibody
FluoroFinder: