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Antibodies

Anti-CDK1 Alexa Fluor[R] 488

Product Sizes
0.1 mg
£312.00
A4-115-0.1MG
About this Product
SKU:
A4-115
Application:
IHC-Paraffin, Immunocytochemistry
CE/IVD:
RUO
translate.label.attr.clone:
POH-1
Conjugate:
Alexa Fluor® 488
Concentration:
0.1 mg/ml
Extra Details:
Cdk1 (cyclin-dependent kinase 1), also known as p34Cdc2 (cell division control protein kinase 2) depends on cyclin A and B and is triggered by a positive feedback loop at the end of G2 phase, which is the key event that initiates mitotic entry. Destruction of cyclin B during metaphase results in inactivation of Cdk1, allowing mitotic exit and cell division. Cdk1 also contributes to the control of DNA replication. Cdk1 can be ihibited by several transcriptional targets of p53, such as p21WAF.
Immunogen:
Bacterially expressed full-length human Cdk1 protein
Isotype:
IgG2a
Reactivities:
Bovine, Human, Non-human Primate
Shipping Conditions:
Blue Ice
Specificity:
The antibody POH-1 specifically detects Cdk1 (p34Cdc2; an intracellular antigen). Staining of Cdk1 reflects the proliferating potential of respective tissue.
Storage Conditions:
2-8[o]C Do not freeze. Protect from light.
Supplier:
Exbio
Type:
Antibody
FluoroFinder: