Anti-Hu CD51/CD61 PE
Product Sizes
100 tests
£278.00
1P-847-100TESTS
About this Product
- SKU:
- 1P-847
- Application:
- Flow Cytometry
- CE/IVD:
- RUO
- translate.label.attr.clone:
- 23C6
- Conjugate:
- R-PE
- Extra Details:
- CD51/CD61 (integrin alpha5beta3), also known as osteoclast functional antigen, serves as a vitronectin receptor, and binds also to fibronectin, fibrinogen, thrombospondin, osteopontin, collagen, and von Willebrand factor. Expression of this antigen increases with melanoma progression. In healthy individuals CD51/CD61 is expressed mainly on osteoclasts, placenta, and endothelial cells, at lower levels on platelets and macrophages.
- Immunogen:
- A cell suspension containing osteoclasts from osteoclastomas
- Isotype:
- IgG1
- Reactivities:
- Avian, Human
- Shipping Conditions:
- Blue Ice
- Specificity:
- The mouse monoclonal antibody 23C6 recognizes an extracellular epitope on CD51/CD61 complex, that is expressed mainly on human osteoclasts, but also e.g. on placenta, or melanoma cell lines. The epitope is native and sensitive to fixation. In chicken this antibody can be used to selectively identify the thrombocytes.
- Storage Conditions:
- 2-8[o]C Do not freeze. Protect from light.
- Supplier:
- Exbio
- Type:
- Antibody
- FluoroFinder:
