Anti-Hu CD146 PE
Product Sizes
25 tests
£159.00
1P-783-25TESTS
100 tests
£278.00
1P-783-100TESTS
About this Product
- SKU:
- 1P-783
- Application:
- Flow Cytometry
- CE/IVD:
- RUO
- translate.label.attr.clone:
- P1H12
- Conjugate:
- R-PE
- Extra Details:
- CD146, also known as MCAM (melanoma cell adhesion molecule) or MUC18, is a heavily glycosylated transmembrane glycoprotein with more than 50% of the mass from carbohydrates. It is expressed on epithelial and endothelial cells, fibroblasts, multipotent mesenchymal stromal cells, activated T cells and activated keratinocytes, and on some cancer cells, especially melanoma. The presence of CD146 on circulating blood cells has been confined to the activated T cells rather than circulating endothelial cells. CD146 mediates heterophilic cell adhesion and regulates monocyte transendothelial migration.
- Immunogen:
- cultured human umbilical cells
- Isotype:
- IgG1
- Reactivities:
- Canine, Human, Mouse, Rabbit
- Shipping Conditions:
- Blue Ice
- Specificity:
- The mouse monoclonal antibody P1H12 recognizes an extracellular epitope of CD146, a 118 kDa transmembrane glycoprotein expressed on epithelial and endothelial cells, fibroblasts, multipotent mesenchymal stromal cells, melanoma cells, activated T cells and activated keratinocytes.
- Storage Conditions:
- 2-8[o]C Do not freeze. Protect from light.
- Supplier:
- Exbio
- Type:
- Antibody
- FluoroFinder:
