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Antibodies

Anti-Hu CD195 PE

Product Sizes
25 tests
£159.00
1P-707-25TESTS
100 tests
£278.00
1P-707-100TESTS
About this Product
SKU:
1P-707
Application:
Flow Cytometry
CE/IVD:
RUO
translate.label.attr.clone:
T21/8
Conjugate:
R-PE
Extra Details:
CD195 / CCR5 (also known as CKR-5) is a receptor for inflammatory CC-chemokines (characterized by a pair of adjacent cysteine residues), such as MIP-1 alpha, MIP-1 beta, or RANTES. It is a G protein-associated seven-pass transmembrane protein expressed on resting T cells with memory/effector phenotype, monocytes, macrophages and immature dendritic cells. This chemokine receptor regulates the activation and directed migration of leukocytes. Importantly, along with CD4, CD195 / CCR5 functions as a major receptor for HIV. Their ligand is the viral glycoprotein gp120.
Immunogen:
CCR5 peptide (Met1-Lys22) KLH conjugate
Isotype:
IgG1, kappa
Reactivities:
Human
Shipping Conditions:
Blue Ice
Specificity:
The mouse monoclonal antibody T21/8 recognizes an extracellular epitope on the N-teminus of CD195, an approximately 45 kDa G-protein coupled receptor 1 family protein expressed on resting T cells, monocytes, macrophages, and immature dendritic cells.
Storage Conditions:
2-8[o]C Do not freeze. Protect from light.
Supplier:
Exbio
Type:
Antibody
FluoroFinder: