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Antibodies

Anti-Rt CD28 PE

Product Sizes
0.025 mg
£138.00
1P-655-0.025MG
0.1 mg
£235.00
1P-655-0.1MG
About this Product
SKU:
1P-655
Application:
Flow Cytometry
CE/IVD:
RUO
translate.label.attr.clone:
JJ319
Conjugate:
R-PE
Concentration:
0.5 mg/ml
Extra Details:
CD28 is the critical T cell costimulatory receptor which provides to the cell the important second activation signal by binding CD80 and CD86 that are expressed by antigen presenting cells. Besides its costimulation role CD28 functions in preventing T cells from anergic hyporesponsive state or from undergoing premature apoptotic cell death. CD28 is also expressed on human fetal NK cells and some NK cell lines, whereas on murine NK cells the CD28 expression is much broader.
Immunogen:
Mouse A20J B lymphoma cells transfected with rat CD28
Isotype:
IgG1, kappa
Reactivities:
Rat
Shipping Conditions:
Blue Ice
Specificity:
The mouse monoclonal antibody JJ319 reacts with an extracellular epitope of CD28, a disulfide-linked homodimeric type I glycoprotein (monomer of Mw 44 kDa) which is a critical costimulatory receptor of T cells.
Storage Conditions:
2-8[o]C Do not freeze. Protect from light.
Supplier:
Exbio
Type:
Antibody
FluoroFinder: