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Antibodies

Anti-NTAL PE

Product Sizes
0.025 mg
£224.00
1P-374-0.025MG
0.1 mg
£407.00
1P-374-0.1MG
About this Product
SKU:
1P-374
Application:
Flow Cytometry
CE/IVD:
RUO
translate.label.attr.clone:
NAP-07
Conjugate:
R-PE
Concentration:
0.1 mg/ml
Extra Details:
NTAL (non-T cell activation linker), also known as LAB (linker for activation of B cells), is a 30 kDa double-palmitoylated transmembrane adaptor protein expressed by B cells, NK cells, mast cells and macrophages. It is a negative regulator of early stages of BCR-dependent B cell signaling and serves as a negative regulator also in mast cells. However, in mast cells, NTAL also contributes to some activation processes, partially overlapping with LAT function.
Immunogen:
Recombinant cytoplasmic domain (aa 91-243) of human NTAL.
Isotype:
IgG1
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Specificity:
The antibody NAP-07 reacts with an intracellular epitope of Non-T cell activation linker (NTAL), also known as LAB (linker of activated B cells), a 25 - 30 kDa transmembrane adaptor protein associating with lipid raft components in the plasma membrane of B lymphocytes, NK cells and myeloid cells.
Storage Conditions:
2-8[o]C Do not freeze. Protect from light.
Supplier:
Exbio
Type:
Antibody
FluoroFinder: