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Antibodies

Anti-Hu CD253 PE

Product Sizes
0.025 mg
£159.00
1P-316-0.025MG
0.1 mg
£278.00
1P-316-0.1MG
About this Product
SKU:
1P-316
Application:
Flow Cytometry
CE/IVD:
RUO
translate.label.attr.clone:
2E5
Conjugate:
R-PE
Concentration:
0.1 mg/ml
Extra Details:
Human CD253 / TRAIL (TNF-related apoptosis inducing ligand), also called Apo2, is a type II membrane protein from the TNF family. TRAIL is a cytotoxic protein which activates rapid apoptosis in tumor cells, but not in normal cells. TRAIL-induced apotosis, is achieved through binding to two dealth-signaling receptors, DR4 (CD261 / TRAIL-R1) and DR5 (CD262 / TRAIL-R2).
Immunogen:
Recombinant soluble fragment (aa 95-281) of human TRAIL.
Isotype:
IgG1
Reactivities:
Human
Shipping Conditions:
Blue Ice
Specificity:
The antibody 2E5 reacts with an extracellular epitope within C-terminal half of TRAIL (APO-2L), a 21 kDa cytotoxic protein, activator of rapid apoptosis in tumor cells. TRAIL is mainly expressed in spleen, lung, prostate and also in many other tissues.
Storage Conditions:
2-8[o]C Do not freeze. Protect from light.
Supplier:
Exbio
Type:
Antibody
FluoroFinder: