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Antibodies

Anti-Hu CD52 FITC

Product Sizes
100 tests
£235.00
1F-878-100TESTS
About this Product
SKU:
1F-878
Application:
Flow Cytometry
CE/IVD:
RUO
translate.label.attr.clone:
4C8
Conjugate:
FITC
Extra Details:
CD52 (CAMPATH-1, HE5) is a highly glycosylated GPI-anchored 21-28 kDa glycopeptide which is present at high levels on lymphocytes, macrophages, epithelial cells of male reproductive tract and mature sperm. Its 12-amino acid beckbone carries a complex N-linked carbohydrate moiety, which differs between sperm and leukocyte CD52, as well as the GPI anchor does. CD52 can be acquired by sperm cells from seminal plasma, where it is released by epithelial cells. Although CD52 is not an essential T-cell costimulator, its triggering results in activation of normal human T cells. CD52 is a very good target for antibody/complement-mediated cell lysis.
Immunogen:
human lymphocytes
Isotype:
IgG3
Reactivities:
Human
Shipping Conditions:
Blue Ice
Specificity:
The mouse monoclonal antibody 4C8 recognizes CD52, a GPI-anchored glycopeptide expressed on the surface of lymphocytes, macrophages, epithelial cells of male reproductive tract, and mature sperms.
Storage Conditions:
2-8[o]C Do not freeze. Protect from light.
Supplier:
Exbio
Type:
Antibody
FluoroFinder: