Anti-Ms CD45R FITC
Product Sizes
0.025 mg
£78.00
1F-715-0.025MG
0.1 mg
£116.00
1F-715-0.1MG
About this Product
- SKU:
- 1F-715
- Application:
- Flow Cytometry
- CE/IVD:
- RUO
- translate.label.attr.clone:
- RA3-6B2
- Conjugate:
- FITC
- Concentration:
- 0.5 mg/ml
- Extra Details:
- CD45R, also known as B220, is a receptor-type protein tyrosine phosphatase glycoprotein. It is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases, promotes cell survival by modulating integrin-mediated signal transduction pathway and is also involved in DNA fragmentation during apoptosis. CD45R expression also identifies a subset of murine bone marrow cells able to form osteoclast-like cells.
- Immunogen:
- Abelson murine leukemia virus-induced pre-B tumor cells
- Isotype:
- IgG2a, kappa
- Reactivities:
- Feline, Human, Mouse
- Shipping Conditions:
- Blue Ice
- Specificity:
- The rat monoclonal antibody RA3-6B2 recognizes an extracellular epitope on CD45R, which is expressed at all developmental stages of B cells, including activated B cells, but also on subsets of NK and T cells. T cells detected by this antibody are supposed to be in activated state.
- Storage Conditions:
- 2-8[o]C Do not freeze. Protect from light.
- Supplier:
- Exbio
- Type:
- Antibody
- FluoroFinder:
