Anti-Ms MHC Class II FITC
Product Sizes
0.1 mg
£202.00
1F-621-0.1MG
About this Product
- SKU:
- 1F-621
- Application:
- Flow Cytometry
- CE/IVD:
- RUO
- translate.label.attr.clone:
- M5/114
- Conjugate:
- FITC
- Concentration:
- 0.5 mg/ml
- Extra Details:
- MHC (major histocompatibility complex) class II molecules are transmembrane glycoproteins expressed on the surface of professional antigen-presenting cells, such as macrophages, dendritic cells and B cells. Before their exposition on the cell surface, the MHC class II molecules react with endocytosed exogenous antigens, which are then presented to the T cells. The antigen-binding grove between MHC class II alpha and beta chain is open at both ends and is 15-24 amino acid residues long.
- Immunogen:
- Activated C57BL/6 mouse spleen cells
- Isotype:
- IgG2b
- Reactivities:
- Mouse
- Shipping Conditions:
- Blue Ice
- Specificity:
- The rat monoclonal antibody M5/114 reacts with murine MHC class II glycoproteins. It recognizes a shared extracellular determinant on I-Ab, I-Ad, I-Aq, and I-Ed, I-Ek alloantigens, but it does not react with I-Af, I-Ak, I-As. This antibody can inhibit I-A-restricted T cell responses of the H-2b, H-2d, H-2q, H-2u but not H-2f, H-2k, H-2s haplotypes.
- Storage Conditions:
- 2-8[o]C Do not freeze. Protect from light.
- Supplier:
- Exbio
- Type:
- Antibody
- FluoroFinder:
