Anti-Hu CD162 FITC
Product Sizes
25 tests
£138.00
1F-603-25TESTS
100 tests
£235.00
1F-603-100TESTS
About this Product
- SKU:
- 1F-603
- Application:
- Flow Cytometry
- CE/IVD:
- RUO
- translate.label.attr.clone:
- TC2
- Conjugate:
- FITC
- Extra Details:
- CD162 (P-selectin glycoprotein ligand-1, PSGL-1) is a sialomucin constitutively expressed as a disulfide-linked homodimer of two 120 kDa subunits on the surface of circulating leukocytes. CD162 serves as a ligand for P- E- and L-selectin, with the highest affinity for P-selectin. It is thus involved in leukocyte rolling at the endothelial surfaces, prerequisite for firm leukocyte adhesion and subsequent transendothelial migration. CD162 also mediates leukocyte-platelet adhesion and interleukocyte contacts. Whereas serving as an adhession molecule on mature leukocytes, CD162 is a potent negative regulator of human hematopoietic progenitors.
- Immunogen:
- Human thymocytes
- Isotype:
- IgG1
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Specificity:
- The antibody TC2 reacts with an extracellular epitope of CD162, a 220 kDa type I integral membrane protein expressed as disulfide-linked homodimer (sialomucin family). CD162 is present on the most peripheral blood T lymphocytes, monocytes, granulocytes; it is also expressed on a subpopulation of B lymphocytes and CD34+ bone marrow cells.
- Storage Conditions:
- 2-8[o]C Do not freeze. Protect from light.
- Supplier:
- Exbio
- Type:
- Antibody
- FluoroFinder:
