Anti-Hu CD271 Biotin
Product Sizes
0.025 mg
£138.00
1B-642-0.025MG
0.1 mg
£235.00
1B-642-0.1MG
About this Product
- SKU:
- 1B-642
- Application:
- Flow Cytometry, IHC-Paraffin, Immunocytochemistry, Immunoprecipitation, Western Blot
- CE/IVD:
- RUO
- translate.label.attr.clone:
- NGFR5
- Conjugate:
- Biotin
- Concentration:
- 1 mg/ml
- Extra Details:
- CD271 / NGFR, also known as p75NGFR or p75NTR, is a 75 kDa low affinity receptor for the NGF (nerve growth factor), BDNF (brain-derived growth factor), and other neurotrophins, such as NT3 and NT4/5. Unlike other members of the tumor necrosis factor receptor superfamily of transmembrane proteins, CD271 has unique intracellular domain structure (lacks catalytic activity) and downstream signaling partners. Triggered by its ligands CD271 affects growth, differentiation, migration and death of the nervous system cells.
- Immunogen:
- Purified CD271 protein isolated from human melanoma cell line A875
- Isotype:
- IgG1
- Reactivities:
- Feline, Human, Non-human Primate, Other Mammal, Rabbit
- Shipping Conditions:
- Blue Ice
- Specificity:
- The mouse monoclonal antibody NGFR5 (originally C34C) recognizes an epitope within ammino acids 1 - 160 of CD271/NGFR, a 75 kDa transmembrane glycoprotein of the TNFR superfamily.
- Storage Conditions:
- 2-8[o]C Do not freeze.
- Supplier:
- Exbio
- Type:
- Antibody
