Anti-Hu CD98 Biotin
Product Sizes
0.025 mg
£138.00
1B-268-0.025MG
0.1 mg
£235.00
1B-268-0.1MG
About this Product
- SKU:
- 1B-268
- Application:
- Flow Cytometry, IHC-Paraffin, Immunoprecipitation
- CE/IVD:
- RUO
- translate.label.attr.clone:
- MEM-108
- Conjugate:
- Biotin
- Concentration:
- 1 mg/ml
- Extra Details:
- CD98 (4F2) is a type II transmembrane glycoprotein which serves as the heavy chain of the heterodimeric amino acid transporters (HATs). CD98, linked to various light chains by disulfide bond, is responsible for cell surface expression and basolateral localization of this transporter complex in polarized epithelial cells and also interacts with beta1 integrins and increases their affinity for ligand. Besides its roles in amino acid transport, CD98 is thus involved in cell fusion and activation. It is implicated in regulation of cellular differentiation, growth and apoptosis.
- Immunogen:
- RAJI human Burkitt's lymphoma cell line
- Isotype:
- IgG1
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Specificity:
- The antibody MEM-108 reacts with an extracellular epitope of CD98, a 125 kDa disulfide-linked heterodimer (80 kDa glycosylated heavy chain + 45 kDa non-glykosylated light chain). CD98 is expressed on T lymphocytes (upon activation) and activated NK cells; it is also present at low levels on B lymphocytes, NK cells, monocytes and platelets.
- Storage Conditions:
- 2-8[o]C Do not freeze.
- Supplier:
- Exbio
- Type:
- Antibody
