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Antibodies

Anti-BCL6 APC

Product Sizes
100 tests
£278.00
1A-867-100TESTS
About this Product
SKU:
1A-867
Application:
Flow Cytometry
CE/IVD:
RUO
translate.label.attr.clone:
IG191E/A8
Conjugate:
APC
Extra Details:
BCL6 is a zinc finger-containing transcription factor, which acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of STAT-dependent IL-4 responses of B cells. On B cells, BCL6 induces proliferation, antibody class switching and affinity maturation, whereas it inhibits their differentiation into plasma cells. On T cells, BCL6 induces their differentiation into T-FH cells.
Immunogen:
pCDNA3 plasmid containing full-length sequence of human BCL6
Isotype:
IgG1
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Specificity:
The mouse monoclonal antibody IG191E/A8 recognizes BCL6, a transcriptional repressor serving as a master regulator of germinal center reaction.
Storage Conditions:
2-8[o]C Do not freeze. Protect from light.
Supplier:
Exbio
Type:
Antibody
FluoroFinder: