Anti-Hu CD266 APC
Product Sizes
0.1 mg
£278.00
1A-755-0.1MG
About this Product
- SKU:
- 1A-755
- Application:
- Flow Cytometry
- CE/IVD:
- RUO
- translate.label.attr.clone:
- ITEM-4
- Conjugate:
- APC
- Concentration:
- 0.1 mg/ml
- Extra Details:
- CD266 / TWEAK R (TNFRSF12A), also known as FN14 (fibroblast growth factor-inducible 14) is a receptor for CD255 / TWEAK, the TNF-like weak inducer of apoptosis. CD266 is expressed on endothelial cells, as well as on some cancer tissues, and plays a role in CD255-induced endothelial cell migration, proliferation, and angiogenesis. The CD255-CD266 interaction, or antibody-mediated triggering of CD266 is also able to induce apoptosis and necrosis in CD266-positive cells (including tumor cells), which might have therapeutic potential.
- Immunogen:
- human CD266-transfected P815 cells
- Isotype:
- IgG2b
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Specificity:
- The mouse monoclonal antibody ITEM-4 recognizes an extracellular epitope of CD266 / TWEAK R, a TNFR superfamily receptor for CD255 / TWEAK, a TNF-like weak inducer of apoptosis.
- Storage Conditions:
- 2-8[o]C Do not freeze. Protect from light.
- Supplier:
- Exbio
- Type:
- Antibody
- FluoroFinder:
