Anti-Hu STRO-1 APC
Product Sizes
0.025 mg
£159.00
1A-649-0.025MG
0.1 mg
£278.00
1A-649-0.1MG
About this Product
- SKU:
- 1A-649
- Application:
- Flow Cytometry
- CE/IVD:
- RUO
- translate.label.attr.clone:
- STRO-1
- Clonality:
- Monoclonal
- Conjugate:
- APC
- Concentration:
- 0.1 mg/ml
- Extra Details:
- STRO-1 is a cell surface antigen expressed by stromal elements in human bone marrow, identified by monoclonal antibody STRO-1. Approximately 10% of mononuclear cells, greater than 95% of which are nucleated erythroid precursors, are STRO-1 positive, whereas the CFU-GM (colony-forming unit granulocyte-macrophage), BFU-E (erythroid burst) and CFU-Mix (mixed colonies) committed progenitor cells are negative. CFU-F (fibroblast colony-forming cells) are present exclusively in the STRO-1 positive population. When plated under long-term bone marrow culture conditions, STRO-1 positive cells generate adherent cell layers containing multiple stromal cell types, including adipocytes, smooth muscle cells, osteoblasts, chondrocytes, and fibroblastic elements. In combination with glycophorin A, STRO-1 is a useful marker for identification of mesenchymal stem cells. STRO-1 and CD117 are markers for osteosarcoma cells.
- Immunogen:
- Human CD34 positive bone marrow cells
- Isotype:
- IgM, lambda
- Reactivities:
- Human, Rabbit, Rat
- Shipping Conditions:
- Blue Ice
- Specificity:
- The mouse monoclonal antibody STRO-1 recognizes an extracellular epitope of the cell surface antigen STRO-1 expressed by bone marrow mesenchymal stromal cells and nucleated erythroid precursors, but not by committed hematopoietic progenitors.
- Storage Conditions:
- 2-8[o]C Do not freeze. Protect from light.
- Supplier:
- Exbio
- Type:
- Antibody: Monoclonal Antibody
- FluoroFinder:
