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Antibodies

Anti-Hu CD97 APC

Product Sizes
100 tests
£278.00
1A-267-100TESTS
About this Product
SKU:
1A-267
Application:
Flow Cytometry
CE/IVD:
RUO
translate.label.attr.clone:
MEM-180
Conjugate:
APC
Extra Details:
CD97 is a G-protein-coupled seven-span transmembrane adhesive receptor that is constitutively expressed on granulocytes and monocytes and rapidly upregulated on T and B cells upon activation. CD97 is produced in alternatively spliced forms and its cellular ligand is CD55 (DAF), which protects various cell types from complement-mediated damage. Interaction of CD97 on leukocytes and CD55 on vessel cells probably facilitate leukocyte activation and migration into the tissues, similarly, CD97 seems to play a role in tumour migration and invasiveness. CD97 is involved in T cell regulation and peripheral granulocyte homeostasis.
Immunogen:
PHA-activated peripheral blood cells
Isotype:
IgG1
Reactivities:
Human
Shipping Conditions:
Blue Ice
Specificity:
The antibody MEM-180 recognizes a unique epitope on CD97, a 75-85 kDa surface glycoprotein of G-protein-coupled receptor family, expressed on activated B and T lymphocytes, monocytes/macrophages, dendritic cells and granulocytes.
Storage Conditions:
2-8[o]C Do not freeze. Protect from light.
Supplier:
Exbio
Type:
Antibody
FluoroFinder: