Anti-Hu CD255 Purified Low Endotoxin
Product Sizes
0.1 mg
£181.00
12-756-0.1MG
About this Product
- SKU:
- 12-756
- Application:
- Cell-based/Functional Assay, Flow Cytometry, Immunohistochemistry
- CE/IVD:
- RUO
- translate.label.attr.clone:
- CARL-1
- Concentration:
- 1 mg/ml
- Extra Details:
- CD255 / TWEAK (TNF-related weak inducer of apoptosis), a type II transmembrane protein expressed as membrane-bound and secreted form, can induce apoptosis in many tissues and cell lines through its receptor CD266 / TWEAK R. On the other hand, in endothelial cells this interaction can induce proliferation and promote angiogenesis including neovascularization of tumours. CD255 can act in a juxtacrine manner to initiate cellular responses, and induces secretion of pro-inflammatory cytokines. Besides CD266, CD255 may also bind to DR3.
- Immunogen:
- human CD255-transfected 2PK-3 cells
- Isotype:
- IgG3, kappa
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Specificity:
- The mouse monoclonal antibody CARL-1 recognizes an extracellular epitope of CD255 / TWEAK, a type II transmembrane protein of the TNF superfamily able to induce apoptosis weakly in many cell types.
- Storage Conditions:
- 2-8[o]C Do not freeze.
- Supplier:
- Exbio
- Type:
- Antibody
