Anti-Ms CD2 Purified Low Endotoxin
Product Sizes
0.1 mg
£170.00
12-716-0.1MG
About this Product
- SKU:
- 12-716
- Application:
- Cell-based/Functional Assay, Flow Cytometry, Immunoprecipitation
- CE/IVD:
- RUO
- translate.label.attr.clone:
- RM2-5
- Concentration:
- 1 mg/ml
- Extra Details:
- CD2 belongs to T lymphocyte glycoproteins of immunoglobulin superfamily. Its interaction with CD58 stabilizes adhesion between T cells and antigen presenting or target cells. Relatively low affinity of CD2 to CD58 (as measured in solution) is compensated within the two-dimensional cell-cell interface to provide tight adhesion. Moreover, T cell activation induces increased CD2 expression and its lateral mobility, making easier contact between CD2 and CD58. Subsequently, T cell activation causes fixation of CD58-CD2 at sites of cell-cell contact, thereby strengthening intercellular adhesion. CD2 deficiency reduces intestinal inflammation and helps to control infection.
- Immunogen:
- murine thymocytes
- Isotype:
- IgG2b, lambda
- Reactivities:
- Mouse
- Shipping Conditions:
- Blue Ice
- Specificity:
- The rat monoclonal antibody RM2-5 recognizes an extracellular epitope of CD2, a 50 kDa glycoprotein present on the human peripheral blood T lymphocytes and NK cells; also expressed by all thymocytes.
- Storage Conditions:
- 2-8[o]C Do not freeze.
- Supplier:
- Exbio
- Type:
- Antibody
