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Antibodies

Anti-Ms TCR beta Purified Low Endotoxin

Product Sizes
0.1 mg
£127.00
12-571-0.1MG
About this Product
SKU:
12-571
Application:
Cell-based/Functional Assay, Flow Cytometry, IHC-Frozen, IHC-Paraffin, Immunocytochemistry, Immunoprecipitation
CE/IVD:
RUO
translate.label.attr.clone:
H57-597
Concentration:
1 mg/ml
Extra Details:
The antigen-specific T cell receptor (TCR) is composed of either alpha and beta subunit, or gamma and delta subunit. Majority of T cells present in the blood, lymph and secondary lymphoid organs express TCR alpha/beta heterodimers, whereas the T cells expressing TCR gamma/delta heterodimers are localized mainly in epithelial tissues and at the sites of infection. The subunits of TCR heterodimers are covalently bonded and in the endoplasmic reticulum they associate with CD3 subunits to form functional TCR-CD3 complex. Lack of expression of any of the chains is sufficient to stop cell surface expression.
Immunogen:
Affinity purified TCR from DO-11.10 T cell hybridoma
Isotype:
IgG2b, kappa
Reactivities:
Mouse
Shipping Conditions:
Blue Ice
Specificity:
The Armenian hamster monoclonal antibody H57-597 reacts specifically with an extracellular epitope on beta subunit of TCR alpha/beta. This antibody does not crossreact with TCR gamma/delta type and has been used as TCR alpha/beta phenotypic marker.
Storage Conditions:
2-8[o]C Do not freeze.
Supplier:
Exbio
Type:
Antibody