Anti-Hu CD253 Purified Low Endotoxin
Product Sizes
0.1 mg
£235.00
12-316-0.1MG
About this Product
- SKU:
- 12-316
- Application:
- Cell-based/Functional Assay, Flow Cytometry
- CE/IVD:
- RUO
- translate.label.attr.clone:
- 2E5
- Concentration:
- 1 mg/ml
- Extra Details:
- Human CD253 / TRAIL (TNF-related apoptosis inducing ligand), also called Apo2, is a type II membrane protein from the TNF family. TRAIL is a cytotoxic protein which activates rapid apoptosis in tumor cells, but not in normal cells. TRAIL-induced apotosis, is achieved through binding to two dealth-signaling receptors, DR4 (CD261 / TRAIL-R1) and DR5 (CD262 / TRAIL-R2).
- Immunogen:
- Recombinant soluble fragment (aa 95-281) of human TRAIL.
- Isotype:
- IgG1
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Specificity:
- The antibody 2E5 reacts with an extracellular epitope within C-terminal half of TRAIL (APO-2L), a 21 kDa cytotoxic protein, activator of rapid apoptosis in tumor cells. TRAIL is mainly expressed in spleen, lung, prostate and also in many other tissues.
- Storage Conditions:
- 2-8[o]C Do not freeze.
- Supplier:
- Exbio
- Type:
- Antibody
