Anti-Hu CD276 Purified
Product Sizes
0.1 mg
£192.00
11-963-0.1MG
About this Product
- SKU:
- 11-963
- Application:
- ELISA, Flow Cytometry, IHC-Frozen
- CE/IVD:
- RUO
- translate.label.attr.clone:
- 7-517
- Concentration:
- 1 mg/ml
- Extra Details:
- CD276 (B7H3) is a type I transmembrane glycoprotein expressed on dendritic cells, osteoblasts, sinonasal epithelium, and upon activation (by inflammatory cytokines) in monocytes, NK cells, T cells and B cells. Although it has been described also as a costimulatory ligand, its major role seems to be inhibitory. It regullates T cell proliferation and functions, and may provide certain tumors with protection against NK cells. CD276 can be used as a marker of neuroblastoma cells in the bone marrow, which is the primary site of neuroblastoma relapse.
- Immunogen:
- monocyte-derived dendritic cells
- Isotype:
- IgG1, kappa
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Specificity:
- The mouse monoclonal antibody 7-517 recognizes an extracellular epitope of human CD276 (B7H3) transmembrane glycoprotein.
- Storage Conditions:
- 2-8[o]C Do not freeze.
- Supplier:
- Exbio
- Type:
- Antibody
