Anti-Hu CD127 Purified
Product Sizes
0.1 mg
£192.00
11-962-0.1MG
About this Product
- SKU:
- 11-962
- Application:
- Flow Cytometry
- CE/IVD:
- RUO
- translate.label.attr.clone:
- rHIQB010
- Extra Details:
- CD127, a 60-90 kDa type I transmembrane glycoprotein, serves as the alpha subunit of the IL-7 receptor. It heterodimerizes with CD132, which is the common interleukin receptor gamma chain. CD127-mediated signaling promotes cell survival and is essential for lymphocyte development, including V(D)J recombination. Defects in CD127 can cause severe combined immunodeficiency (SCID). It is expressed in common lymphoid progenitors, B and T cell precursors (except CD4/CD8 double positive thymocytes), and mature T cell subpopulations. Majority of CD127-CD4+ T cells are Treg cells.
- Isotype:
- IgG1
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Specificity:
- The recombinant mouse monoclonal antibody rHIQB010 recognizes an extracellular epitope of human CD127, the alpha subunit of IL-7 receptor.
- Storage Conditions:
- 2-8[o]C Do not freeze.
- Supplier:
- Exbio
- Type:
- Antibody
