Anti-Hu CD183 Purified
Product Sizes
0.1 mg
£192.00
11-960-0.1MG
About this Product
- SKU:
- 11-960
- Application:
- Flow Cytometry
- CE/IVD:
- RUO
- translate.label.attr.clone:
- rHIQB005
- Concentration:
- 1 mg/ml
- Extra Details:
- CD184 is a 7-transmembrane G-protein coupled receptor for the C-X-C chemokines SDF-1 (CXCL12), MIG (CXCL9) and IP10 (CXCL10). Alternatively spliced variant CD184B serves as the high affinity receptor for PF4 (CXCL4). CD184 is expressed in hematopoietic cells, vascular endothelium, and neural tissue. It plays important roles in endothelial vascularization and central nervous system development. It can also serve as a primary receptor or a coreceptor for some HIV isolates. CD184 signaling leads to integrin activation, cytoskeletal changes and chemotactic migration.
- Isotype:
- IgG1
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Specificity:
- The recombinant mouse monoclonal antibody rHIQB005 recognizes an extracellular epitope on human chemokine receptor CD184.
- Storage Conditions:
- 2-8[o]C Do not freeze.
- Supplier:
- Exbio
- Type:
- Antibody
