Anti-Hu SIGLEC10 Purified
Product Sizes
0.1 mg
£192.00
11-932-0.1MG
About this Product
- SKU:
- 11-932
- Application:
- ELISA, Immunohistochemistry, Immunoprecipitation
- CE/IVD:
- RUO
- translate.label.attr.clone:
- 5G6
- Concentration:
- 1 mg/ml
- Extra Details:
- SIGLEC10 is a CD33-related receptor of sialoglycans, expressed on eosinophils, monocytes, a subpopulation of NK cells, and at lower level on B cells. Its murine ortholog is Siglec G. SIGLEC10 seems to act as an immunomodulatory receptor, which binds to VAP-1, a glycoprotein expressed on endothelium under inflammatory conditions. Another ligand of SIGLEC10 is CD24, a marker of poorer prognosis in carcinomas.
- Immunogen:
- SIGLEC10 extracellular domain fused with human IgG1 Fc fragment
- Isotype:
- IgG1
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Specificity:
- The mouse monoclonal antibody 5G6 recognizes an extracellular epitope of human SIGLEC10, a sialic acid-binding lectin expressed on subsets of human leucocytes.
- Storage Conditions:
- 2-8[o]C Do not freeze.
- Supplier:
- Exbio
- Type:
- Antibody
