Anti-Hu TCR Valpha24-Jalpha18 Purified
Product Sizes
0.1 mg
£192.00
11-927-0.1MG
About this Product
- SKU:
- 11-927
- Application:
- Flow Cytometry, IHC-Frozen, Immunocytochemistry
- CE/IVD:
- RUO
- translate.label.attr.clone:
- 6B11
- Concentration:
- 1 mg/ml
- Extra Details:
- TCR alpha V24-J18 chain is a marker of invariant NK T cells (iNKT). This chain pairs mostly with TCR beta V11 chain, and together they interact with glycolipide-loaded CD1d. This interaction results in iNKT activation and cytokine production (IFN gamma, IL-4, IL-13), which takes important part in immune regulation and host response to pathogens and cancer(support of both Th1 and Th2 way), although iNKT cells represent less than 1% of total peripheral T cells.
- Isotype:
- IgG1, kappa
- Reactivities:
- Human, Non-human Primate
- Shipping Conditions:
- Blue Ice
- Specificity:
- The mouse monoclonal antibody 6B11 recognizes an extracellular epitope within V alpha 24 J alpha 18 TCR, which is expressed by invariant NK T cells (iNKT).
- Storage Conditions:
- 2-8[o]C Do not freeze.
- Supplier:
- Exbio
- Type:
- Antibody
