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Antibodies

Anti-Hu CD270 Purified

Product Sizes
0.1 mg
£192.00
11-911-0.1MG
About this Product
SKU:
11-911
Application:
ELISA, Flow Cytometry, Immunocytochemistry, Immunoprecipitation, Western Blot
CE/IVD:
RUO
translate.label.attr.clone:
CW10
Concentration:
1 mg/ml
Extra Details:
CD270 is a type I transmembrane protein of the TNFR superfamily, which is expressed on resting T cells, monocytes, and immature dendritic cells. Its ligands, CD258 and CD272, differ in effect on CD270 signaling. Whereas binding to CD258 provides a costimulatory signal, binding to CD272 gives to the cell an inhibitory signal. CD270 also is recognized by herpes simplex glycoprotein D. CD258-CD270 interaction and signaling is implicated in macrophage-derived foam cell-mediated development of atherosclerotic lesions.
Immunogen:
recombinant human CD270
Isotype:
IgG1, kappa
Reactivities:
Human
Shipping Conditions:
Blue Ice
Specificity:
The mouse monoclonal antibody CW10 recognizes an extracellular epitope on CD270, a type I transmembrane protein expressed on resting T cells, monocytes, and immature dendritic cells.
Storage Conditions:
2-8[o]C Do not freeze.
Supplier:
Exbio
Type:
Antibody