Anti-Hu CD335 Purified
Product Sizes
0.1 mg
£192.00
11-853-0.1MG
About this Product
- SKU:
- 11-853
- Application:
- Flow Cytometry
- CE/IVD:
- RUO
- translate.label.attr.clone:
- 9E2
- Concentration:
- 1 mg/ml
- Extra Details:
- CD335 is a type I transmembrane glycoprotein, which serves as one of natural cytotoxicity receptors, and represents major receptor informing NK cells that they should kill particular virus-infected or tumor cell. Its sialic acids residues are involved in recognition of viral hemagglutinins, similarly it recognizes heparan sulphate proteoglycans on the surface of tumor cells. CD335 transfers the signal downstream via association with CD3 zeta chain, that contains intracellular ITAM motifs. Expression of CD335, a specific marker of NK cells (both resting and activated), is down regulated by cortisol, and up-regulated by prolactin.
- Immunogen:
- fusion protein of human CD335 and Fc part of IgG
- Isotype:
- IgG1
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Specificity:
- The mouse monoclonal antibody 9E2 recognizes an extracellular epitope of human CD335, a transmembrane glycoprotein, serving as a natural cytotoxicity receptor against virus-infected or cancer cells.
- Storage Conditions:
- 2-8[o]C Do not freeze.
- Supplier:
- Exbio
- Type:
- Antibody
