Anti-Hu SIGLEC8 Purified
Product Sizes
0.1 mg
£192.00
11-846-0.1MG
About this Product
- SKU:
- 11-846
- Application:
- ELISA, Flow Cytometry, Immunoprecipitation
- CE/IVD:
- RUO
- translate.label.attr.clone:
- 7C9
- Concentration:
- 1 mg/ml
- Extra Details:
- SIGLEC8 is a sialic acid binding lectin similar to CD33. In its cytoplasmic comain it contains an immunoreceptor tyrosine-based inhibitory motif (ITIM), and a motive similar to a binding site for SLAM-associated protein. SIGLEC8 is expressed e.g. in lymph nodes and spleen. It is an eosinophil marker, although it can be found also on the surface of mast cells. Crosslinking of SIGLEC8 leads to apoptosis. Soluble form of SIGLEC8 can be foud in human serum, especially in case of eosinophil-associated diseases.
- Immunogen:
- Extracellular domain of human SIGLEC8 fused with Fc fragment of human IgG1
- Isotype:
- IgG1
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Specificity:
- The mouse monoclonal antibody 7C9 recognizes an extracellular epitope of SIGLEC8, an eosinophil marker, expressed e.g. in lymph nodes and spleen.
- Storage Conditions:
- 2-8[o]C Do not freeze.
- Supplier:
- Exbio
- Type:
- Antibody
