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Antibodies

Anti-HDAC6 Purified

Product Sizes
0.1 mg
£192.00
11-840-0.1MG
About this Product
SKU:
11-840
Application:
ELISA, Immunocytochemistry, Western Blot
CE/IVD:
RUO
translate.label.attr.clone:
3D2
Concentration:
1 mg/ml
Extra Details:
Histone deacetylase 6 (HDAC6), like other histone deacetylases, affects gene expression by regulation of chromatin remodeling. HDAC6 contains an internal duplication of two catalytic domains which appear to function independently of each other. Besides histones, HDAC6 deacetylates also other substrates including alpha tubulin and HSP90 alpha, and is involved in protein trafficking and degradation, as well as in affecting of cell shape and migration. Deregulation of HDAC6 expression and activity is associated with many diseases.
Immunogen:
human HDAC6
Isotype:
IgG1, kappa
Reactivities:
Human
Shipping Conditions:
Blue Ice
Specificity:
The mouse monoclonal antibody 3D2 recognizes D2 domain of human histone deacetylase 6 (HDAC6; intracellular antigen), amino acids 471-481.
Storage Conditions:
2-8[o]C Do not freeze.
Supplier:
Exbio
Type:
Antibody