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Antibodies

Anti-Hu CD129 Purified

Product Sizes
0.025 mg
£111.00
11-788-0.025MG
0.1 mg
£181.00
11-788-0.1MG
About this Product
SKU:
11-788
Application:
ELISA, Flow Cytometry
CE/IVD:
RUO
translate.label.attr.clone:
AH9R7
Concentration:
1 mg/ml
Extra Details:
CD129 serves as the high affinity alpha subunit of IL-9 receptor. It associates with CD132, the common gamma chain shared by receptors of many different cytokines. CD129 is expressed at low levels by T and B cells, blood cell progenitors, eosinophils, mast cells, epithelial cells, muscle cells and neurons. Its signaling (through JAK/STAT pathways) results in proliferative and anti-apoptotic response, which is critical e.g. for intrathymic T cell development and survival of various cell types. The gene for CD129 is located at the pseudoautosomal regions of X and Y chromosomes and it may be related with the development of asthma.
Immunogen:
Human CD129-transfected cell line
Isotype:
IgG2b, kappa
Reactivities:
Human
Shipping Conditions:
Blue Ice
Specificity:
The mouse monoclonal antibody AH9R7 recognizes an extracellular epitope of CD129 / IL-9R alpha, a 57 kDa type I transmembrane glycoprotein expressed at low levels by lymphocytes, blood cell progenitors, eosinophils, mast cells, epithelial cells, muscle cells and neurons.
Storage Conditions:
2-8[o]C Do not freeze.
Supplier:
Exbio
Type:
Antibody