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Antibodies

Anti-Ms LPAM-1 Purified

Product Sizes
0.025 mg
£84.00
11-747-0.025MG
0.1 mg
£127.00
11-747-0.1MG
About this Product
SKU:
11-747
Application:
Flow Cytometry, IHC-Frozen, Immunoprecipitation
CE/IVD:
RUO
translate.label.attr.clone:
DATK32
Concentration:
1 mg/ml
Extra Details:
Integrin alpha 4 / beta 7 (CD49d / Ly69) , also known as LPAM-1 (Llmphocyte Peyer's patch adhesion molecule 1), is a heterodimeric (150 kDa / 130 kDa) integrin complex which mediates lymphocyte homing to Peyer's patch high endothelial venules and to the intestinal lamina propria. It is expressed primarily on mucosal lymphocytes, but is also present on NK cells and eosinophils. Ligands of LPAM-1 are MAdCAM-1, VCAM-1, and fibronectin, but the alpha 4 subunit (CD49d) can mediate also homotypic adhesion.
Immunogen:
TK1 cells
Isotype:
IgG2a, kappa
Reactivities:
Mouse
Shipping Conditions:
Blue Ice
Specificity:
The rat monoclonal antibody DATK32 recognizes an extracellular epitope of integrin alpha 4 (CD49d) and integrin beta7 (Ly69) components of mouse LPAM-1 complex, which is expressed on the majority of peripheral lymphocytes, as well as on subsets of thymocytes and bone marrow cells.
Storage Conditions:
2-8[o]C Do not freeze.
Supplier:
Exbio
Type:
Antibody