Anti-Ms CD106 Purified
Product Sizes
0.025 mg
£84.00
11-742-0.025MG
0.1 mg
£127.00
11-742-0.1MG
About this Product
- SKU:
- 11-742
- Application:
- Flow Cytometry, IHC-Frozen, Immunoprecipitation
- CE/IVD:
- RUO
- translate.label.attr.clone:
- 429 (MVCAM.A)
- Concentration:
- 1 mg/ml
- Extra Details:
- CD106 / VCAM-1 (vascular cell adhesion molecule-1) is an Ig-like cell surface adhesion molecule binding VLA-4 integrin. VCAM-1 is a potent T cell costimulatory molecule taking part in their positive selection and survival, as well as in adhesion, transendothelial migration and activation of peripheral T cells. VCAM-1 is also involved in endothelial cell-cell contacts. Whereas VCAM-1 normally mediates leukocyte extravasion to sites of tissue inflammation, tumour cells can use overexpressed VCAM-1 to escape T cell immunity.
- Immunogen:
- Murine preadipose cell line PA6
- Isotype:
- IgG2a, kappa
- Reactivities:
- Mouse
- Shipping Conditions:
- Blue Ice
- Specificity:
- The rat monoclonal antibody 429 (also known as MVCAM.A) recognizes an extracellular epitope of murine CD106, a 100-110 kDa type I membrane protein of the immunoglobulin superfamily, a crucial mediator of leukocyte adhesion, and a costimulation molecule.
- Storage Conditions:
- 2-8[o]C Do not freeze.
- Supplier:
- Exbio
- Type:
- Antibody
