Anti-Ms CD44 Purified
Product Sizes
0.1 mg
£127.00
11-624-0.1MG
About this Product
- SKU:
- 11-624
- Application:
- Flow Cytometry, IHC-Frozen, IHC-Paraffin, Immunocytochemistry, Immunoprecipitation, Western Blot
- CE/IVD:
- RUO
- translate.label.attr.clone:
- IM7
- Concentration:
- 1 mg/ml
- Extra Details:
- CD44 is a transmembrane glycoprotein expressed on the surface of most cells, which serves as a receptor for hyaluronan. CD44 mediates angiogenesis, cell adhesion, proliferation and migration, it is thus important for lymphocyte activation, recirculation and homing, it can thus serve e.g. as a modulator of macrophage recruitment in response to pathogen. Although CD44 functions are essential for physiological activities of normal cells, elevated CD44 expression correlates with poor prognosis in many carcinomas, facilitating tumour growth and metastasis, antiapoptosis and directional motility of cancer cells.
- Immunogen:
- Dexamethasone-induced cells of the SJL mouse spontaneous myeloid leukemia M1
- Isotype:
- IgG2b, kappa
- Reactivities:
- Canine, Feline, Horse, Human, Mouse
- Shipping Conditions:
- Blue Ice
- Specificity:
- The rat monoclonal antibody IM7 reacts with an extracellular epitope of CD44 antigen (Phagocyte glycoprotein 1), an 80-95 kDa transmembrane glycoprotein (hyaladherin family) present on the most of cells and tissues (leukocytes, endothelial cells, mesenchymal cells, etc.); it is negative on platelets and hepatocytes. The antibody reacts with all isoforms of mouse CD44.
- Storage Conditions:
- 2-8[o]C Do not freeze.
- Supplier:
- Exbio
- Type:
- Antibody
