Anti-PRR7 Purified
Product Sizes
0.025 mg
£159.00
11-617-0.025MG
0.1 mg
£278.00
11-617-0.1MG
About this Product
- SKU:
- 11-617
- Application:
- Immunocytochemistry, Western Blot
- CE/IVD:
- RUO
- translate.label.attr.clone:
- TRAP3/10
- Concentration:
- 1 mg/ml
- Extra Details:
- PRR7/TRAP3 (proline-rich 7, transmembrane adaptor protein 3) is a 28 kDa transmembrane adaptor protein ubiquitously expressed at low level (most in brain). Its amino acid sequence is extremely conserved among mammalian and other species. PRR7/TRAP3 contains potential palmitoylation motif and is found in lipid rafts. It is a part of the complex postsynaptic density fraction in neurons and associates with PSD-95, NMDA receptor and probably other proteins. The intracellular domain of PRR7/TRAP3 contains several tyrosines, a proline-rich sequence, and a C-terminal PDZ-binding motif. So far nothing is known about function of this protein. It may be involved in regulation of some receptor signaling and in formation of neurologic and immunologic synapse.
- Immunogen:
- Recombinant C-terminal half of the intracellular domain of human PRR7/TRAP3 (amino acids 126-253)
- Isotype:
- IgG2a
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Specificity:
- The mouse monoclonal antibody TRAP3/10 recognizes an epitope located in the C-terminal part of the intracellular domain of PRR7/TRAP3 (amino acids 126-253 of human PRR7 / TRAP3), a 28 kDa proline-rich membrane protein presumably associated with NMDA receptor complex.
- Storage Conditions:
- 2-8[o]C Do not freeze.
- Supplier:
- Exbio
- Type:
- Antibody
