Anti-Hu CD140a Purified
Product Sizes
0.025 mg
£121.00
11-589-0.025MG
0.1 mg
£202.00
11-589-0.1MG
About this Product
- SKU:
- 11-589
- Application:
- Flow Cytometry, Immunocytochemistry
- CE/IVD:
- RUO
- translate.label.attr.clone:
- 16A1
- Concentration:
- 1 mg/ml
- Extra Details:
- CD140a / PDGF-RA (platelet-derived growth factor receptor alpha) is a cell surface receptor for members of platelet-derived growth factor family, whose intracellular part contains a tyrosine kinase domain. CD140a forms homodimers, or heterodimerizes with CD140b / PDGF-RB. Whereas CD140b induces in different cell types their proliferation and migration, the role of CD140a is more controversial, with pro-proliferative or anti-proliferative effects. CD140a has early developmental functions, mediates mesodermal cell migration, and later acts in signaling associated in epithelial-mesenchymal interactions.
- Immunogen:
- CD140a-transfected NIH 3T3 cells
- Isotype:
- IgG1, kappa
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Specificity:
- The mouse monoclonal antibody 16A1 recognizes an extracellular epitope of CD140a / PDGF-RA, the 170 kDa alpha chain of platelet-derived growth factor receptor, which is widely expressed on a variety of mesenchymal-derived cells and plays pro-proliferative or anti-proliferative roles in various tumours.
- Storage Conditions:
- 2-8[o]C Do not freeze.
- Supplier:
- Exbio
- Type:
- Antibody
