Anti-UBN1 Purified
Product Sizes
0.025 mg
£138.00
11-565-0.025MG
0.1 mg
£235.00
11-565-0.1MG
About this Product
- SKU:
- 11-565
- Application:
- Immunoprecipitation, Western Blot
- CE/IVD:
- RUO
- translate.label.attr.clone:
- UBN1-02
- Concentration:
- 1 mg/ml
- Extra Details:
- Ubinuclein 1 (UBN1) is a ubiquitously expressed evolutionarily conserved protein which binds to proliferation-promoting genes that are repressed by formation of senescence-associated heterochromatin foci (SAHF). Ubinuclein 1 associates with various transcription factors and with histone methyltransferase activity, is indispensable for SAHF formation and appears to be a regulator of senescence. Although in most cells ubinuclein is localized to the nucleus, in cells forming tight junctions it is recruited to the cell adhesion complexes, dependently on the cell density.
- Immunogen:
- Recombinant protein corresponding to amino acids 1-190 of ubinuclein 1.
- Isotype:
- IgG1, kappa
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Specificity:
- The antibody UBN1-02 recognizes N-terminal part of ubinuclein 1 (UBN1), a widely expressed nuclear and adhesion complex protein. Western blotting analysis reveals UBN1 as a 165 kDa band.
- Storage Conditions:
- 2-8[o]C Do not freeze.
- Supplier:
- Exbio
- Type:
- Antibody
