Anti-GRB2 Purified
Product Sizes
0.025 mg
£138.00
11-554-0.025MG
0.1 mg
£235.00
11-554-0.1MG
About this Product
- SKU:
- 11-554
- Application:
- Western Blot
- CE/IVD:
- RUO
- translate.label.attr.clone:
- PAb (554)
- Concentration:
- 1 mg/ml
- Extra Details:
- Grb2 (growth factor receptor-bound protein 2) is a highly conserved adaptor protein composed of central SH2 domain flanked by two terminal SH3 domains. Grb2 mediates coupling of receptor protein tyrosine kinases to a guanine nucleotide exchange factor Sos, thereby enabling the tyrosine kinases to stimulate activity of Ras and hence of MAP kinase pathway. Grb2 also can bind to receptor protein tyrosine phosphatases and affect their signaling.
- Immunogen:
- Synthetic peptide corresponding to C-terminus of human Grb2 (amino acids 198-217).
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Specificity:
- The polyclonal antibody recognizes Grb2, a highly conserved approximately 26 kDa intracellular adaptor protein. The immunogen has 100% identity between man, cow, rat and mouse.
- Storage Conditions:
- 2-8[o]C Do not freeze.
- Supplier:
- Exbio
- Type:
- Antibody
