Anti-Hu CD11c Purified
Product Sizes
0.025 mg
£116.00
11-529-0.025MG
0.1 mg
£192.00
11-529-0.1MG
About this Product
- SKU:
- 11-529
- Application:
- Flow Cytometry, IHC-Frozen, Immunoprecipitation
- CE/IVD:
- RUO
- translate.label.attr.clone:
- BU15
- Concentration:
- 1 mg/ml
- Extra Details:
- CD11c (p150, alphaX integrin subunit) forms complex with CD18 (beta2 integrin subunit) and is expressed mainly on tissue macrophages and dendritic cells. CD11c binds to complement fragment iC3b, fibrinogen, VCAM-1 and ICAM-2 or e.g. CD90. Like other beta2 integrins, CD11c/CD18 plays roles in cell migration and phagocytosis. Moreover, interaction of CD11c/CD18 with plasminogen regulates plasmin activities, and interaction with heparin counteracts binding of iC3b.
- Immunogen:
- Dendritic cells of synovial fluid
- Isotype:
- IgG1, kappa
- Reactivities:
- Human, Non-human Primate
- Shipping Conditions:
- Blue Ice
- Specificity:
- The antibody BU15 reacts with an extracellular epitope of CD11c (alphaX, p150), a 150 kDa integrin expressed mainly on dendritic cells and tissue macrophages.
- Storage Conditions:
- 2-8[o]C Do not freeze.
- Supplier:
- Exbio
- Type:
- Antibody
