Anti-Clathrin Heavy Chain Purified
Product Sizes
0.025 mg
£143.00
11-526-0.025MG
0.1 mg
£245.00
11-526-0.1MG
About this Product
- SKU:
- 11-526
- Application:
- ELISA, Flow Cytometry, Immunocytochemistry, Immunoprecipitation, Western Blot
- CE/IVD:
- RUO
- translate.label.attr.clone:
- BF-06
- Concentration:
- 1 mg/ml
- Extra Details:
- Clathrin is a submembrane protein that polymerizes into coat-like lattices, which results in membrane invagination. The basic oligomers are composed of three clathrin heavy chain (180 kDa) and three light chain (30 kDa) subunits and the process of polymerization is dynamically regulated by the light chains. Interaction of clathrin with the plasma membrane is mediated by adaptor proteins (AP1-4) specific for different cellular compartments. Another proteins, such as endophilin, epsin and amphiphysin are involved in membrane invagination and clathrin rearrangements. Finally, dynamin functions at the fission stage of clathrin-mediated endocytosis.
- Isotype:
- IgM
- Reactivities:
- Bovine, Human, Mouse, Porcine, Rat
- Shipping Conditions:
- Blue Ice
- Specificity:
- The antibody BF-06 recognizes clathrin heavy chain, an ubiquitously expressed 180 kDa intracellular protein involved in receptor-mediated endocytosis.
- Storage Conditions:
- 2-8[o]C Do not freeze.
- Supplier:
- Exbio
- Type:
- Antibody
