Anti-Hu CD66e Purified
Product Sizes
0.025 mg
£111.00
11-479-0.025MG
0.1 mg
£181.00
11-479-0.1MG
About this Product
- SKU:
- 11-479
- Application:
- Flow Cytometry, IHC-Frozen, IHC-Paraffin, Immunoprecipitation
- CE/IVD:
- RUO
- translate.label.attr.clone:
- CB30
- Concentration:
- 1 mg/ml
- Extra Details:
- The CD66e (CEA; 180-200 kDa) is a member of carcinoembryonic antigens, immunoglobulin supergene family and consists of a single N domain (structural homology to the immunoglobulin variable) and six immunoglobulin constant-like A (A1, A2, A3) and B domains (B1, B2, B3). Human CD66e is heavily glycosylated GPI anchored protein capable of both homophilic and heterophilic adhesion. Disease relevance: The CD66e may play a role in the process of metastasis of cancer cells. CD66e is found in serum and it is clinically used as a tumor marker for early detection of disease due to its expression in adenocarcinomas - potential target of tumor imaging and drug targeting.
- Immunogen:
- Human carcinoembryonic antigen (CEA; CEACAM5)
- Isotype:
- IgG1
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Specificity:
- The mouse monoclonal antibody CB30 recognizes CD66e (CEA; 180-200 kDa), an extracellular cell surface-bound carcinoembryonic antigen mainly expressed on epithelial cells.
- Storage Conditions:
- 2-8[o]C Do not freeze.
- Supplier:
- Exbio
- Type:
- Antibody
