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Antibodies

Anti-Hu CD235ab Purified

Product Sizes
0.025 mg
£116.00
11-419-0.025MG
0.1 mg
£192.00
11-419-0.1MG
About this Product
SKU:
11-419
Application:
Agglutination, Flow Cytometry, IHC-Frozen, IHC-Paraffin
CE/IVD:
RUO
translate.label.attr.clone:
HIR2
Concentration:
1 mg/ml
Extra Details:
CD235a (glycophorin A, GPA) is a transmembrane sialoglycoprotein expressed on erythrocytes and their precursors. Similarly to CD235b (glycophorin B, GPB), these molecules provide the cells with a large mucin-like surface, which minimalizes aggregation between erythrocytes in the circulation. GPA is the carrier of blood group M and N specificities, while GPB accounts for S, s and U specificities. CD235a is a receptor of Hsa, a Streptococcus adhesin.
Immunogen:
Synthetic peptide (Human, N-terminal)
Isotype:
IgG2b
Reactivities:
Human
Shipping Conditions:
Blue Ice
Specificity:
The mouse monoclonal antibody HIR2 recognizes an epitope within the N-terminal (extracellular) portion of CD235a (glycophorin A) and CD235b (glycophorin B). Its antigen is expressed on early erythroblasts, late erythroblasts, erythroblasts, mature erythrocytes and the cells of erythroid cell lines K562 and HEL, but not on all other cells.
Storage Conditions:
2-8[o]C Do not freeze.
Supplier:
Exbio
Type:
Antibody