Anti-Ms Blnk Purified
Product Sizes
0.025 mg
£138.00
11-411-0.025MG
0.1 mg
£235.00
11-411-0.1MG
About this Product
- SKU:
- 11-411
- Application:
- Western Blot
- CE/IVD:
- RUO
- translate.label.attr.clone:
- PAb (411)
- Concentration:
- 1 mg/ml
- Extra Details:
- SLP65 / BLNK (SH2 domain-containing leukocyte-specific phosphoprotein of 65 kDa; B cell linker protein), also known as BASH, is an adaptor protein that plays key role in B cell activation initiated by cross-linking the B cell receptor (BCR). Phosphorylated by Syk tyrosine kinase, SLP65 serves as a scaffold for Btk tyrosine kinase, Vav1 guanine nucleotide exchange factor, phospholipase C gamma2, as well as Grb2 and Nck adaptor proteins; thus represents a central linker protein that bridges the BCR-associated kinases with a multitude of signaling pathways.
- Immunogen:
- A fusion protein representing amino acids 171-356 of human BLNK.
- Reactivities:
- Mouse
- Shipping Conditions:
- Blue Ice
- Specificity:
- The polyclonal antibody reacts with mouse SLP65 / BLNK, a cytosolic adaptor protein identified as two phosphoproteins migrating at 68 and 70 kDa in SDS/PAGE (alternatively spliced forms of human SLP65).
- Storage Conditions:
- 2-8[o]C Do not freeze.
- Supplier:
- Exbio
- Type:
- Antibody
