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Antibodies

Anti-NTAL Purified

Product Sizes
0.025 mg
£138.00
11-373-0.025MG
0.1 mg
£235.00
11-373-0.1MG
About this Product
SKU:
11-373
Application:
IHC-Paraffin, Immunoprecipitation, Western Blot
CE/IVD:
RUO
translate.label.attr.clone:
NAP-03
Concentration:
1 mg/ml
Extra Details:
NTAL (non-T cell activation linker), also known as LAB (linker for activation of B cells), is a 30 kDa double-palmitoylated transmembrane adaptor protein expressed by B cells, NK cells, mast cells and macrophages. It is a negative regulator of early stages of BCR-dependent B cell signaling and serves as a negative regulator also in mast cells. However, in mast cells, NTAL also contributes to some activation processes, partially overlapping with LAT function.
Immunogen:
Peptide corresponding to aa 196-212 of human NTAL coupled to KLH.
Isotype:
IgG2a
Reactivities:
Human
Shipping Conditions:
Blue Ice
Specificity:
The antibody NAP-03 recognizes a defined intracellular epitope (aa 196-212) of human Non-T cell Activation Linker (NTAL), also known as LAB (linker of activated B cells), a 30 kDa transmembrane adaptor protein associating with lipid raft components in the plasma membrane of B cells, NK cells and myeloid cells.
Storage Conditions:
2-8[o]C Do not freeze.
Supplier:
Exbio
Type:
Antibody